Centella asiatica

Kingdom: Plantae
Family: Apiaceae
Group: Angiosperms
Common name: Indian Pennywort
Synonymous names: Hydrocotyle asiatica, Centella asiatica, Cantella asiatica, Centaurea asiatica
System of medicine: Ayurveda, Homeopathy, Siddha, Sowa Rigpa, Unani
IUCN Red List category: Least Concern
IMPPAT Plant identifier: IMPPAT3_PLTID000641

More Information:
Plant - Phytochemical associations


Clinical trials related to Centella asiatica


Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
The effect of Centella asiatica L. on cognitive disorders in MSThe effect of Centella asiatica L. on cognitive impairments in patients with multiple sclerosis (MS)IRCT20161108030776N5
The Efficacy of Standardized Extract of Centella asiatica ECa 233 on the Healing effect after Erbium-YAG 2,940 nm laser: A Double-Blinded randomized control trialThe Efficacy of Standardized Extract of Centella asiatica ECa 233 on the Healing effect after Erbium-YAG 2,940 nm laser: A Double-Blinded randomized control trialTCTR20180927001
Efficacy and safety assessment of Centella asiatica as a herbal dietary supplement to reduce blood sugar levels in type 2 diabetes patients in ThailandEfficacy and safety assessment of Centella asiatica as a herbal dietary supplement to reduce blood sugar levels in type 2 diabetes patients in ThailandTCTR20221219003
Comparison of care for incontinence associated dermatitis between zinc oxide mixed petroleum jelly with Centella asiatica mixed with Aloe Vera along on risk level, time of healing ,Severity level, Skin surface pH and skin moisture among older patients in semi-intensive medical care unitsComparison of care for incontinence associated dermatitis between zinc oxide mixed petroleum jelly with Centella asiatica mixed with Aloe Vera along on risk level, time of healing ,Severity level, Skin surface pH and skin moisture among older patients in semi-intensive medical care units: A randomized controlled trialTCTR20240910009
Comparative evaluation of Brahmi,Curry leaf mouthwash formulation with Chlorhexidine mouthwash in treatment of Chronic infection of gumsComparative evaluation of Centella asiatica ,Murraya koenigii mouthwash formulation with Chlorhexidine mouthwash in treatment of Chronic gingivitis: A prospective randomized controlled double blinded clinical trialCTRI/2019/01/016967
Bioadhesive herbal mouthwashes for management of radiation induced oral mucositis in Head & Neck cancer patients.Comparative effectiveness of benzydamine against the bioadhesive mouthwashes of Centella asiatica & Solanum nigrum Linn in the management of oral mucositis. A Double Blinded Randomized controlled trial.CTRI/2023/06/054012
Effect of Centella Asiatica on Xerotic Skin in Diabetes Mellitus Type 2Effect of Centella Asiatica on Xerotic Skin in Diabetes Mellitus Type 2: a Study on N(6)-Carboxymethyl-lysine, Interleukin 1-a, Dan Superoxide Dismutase in Stratum CorneumNCT03815305
Evaluation of Effects on Skin Quality of a Centella Asiatica Extracellular Vesicle-based Skin Care Formulation.Evaluation of the Skin Care Effects of Kristen Claire Supreme Rejuvenation EssenceNCT06850935
The Effects of Centella Asiatica on Diabetic Foot UlcersComparison of the Effectiveness of Centella Asiatica and Placebo on Infection Control and Foot Ulcer Healing in Diabetic PatientsIRCT20240913063024N1
Centella Asiatica in Older AdultsEffect of Centella Asiatica on Vascular Endothelial Function in Older AdultsNCT06472791
Centella Asiatica Selected Triterpenes (CAST) for Diabetic NeuropathyCentella Asiatica Triterpene Extract for Diabetic Neuropathy -- a Pilot StudyNCT00608439
Efficacy and safety assessment of Centella asiatica as an herbal dietary supplement to reduce blood sugar levels in type II diabetes patients in Thailand.Efficacy and safety assessment of Centella asiatica as an herbal dietary supplement to reduce blood sugar levels in type II diabetes patients in Thailand.TCTR20230928003
Effect of Centella asiatica on burning treatmentEffects of topical ointment of Centella asiatica on partial thickness burning (A randomized clinical trial)IRCT2013100614915N1
Pharmacokinetics of Centella Asiatica in the ElderlyA Pharmacokinetic Study of Centella Asiatica in the ElderlyNCT03929250
Effect of centella asiatica on pain and wound healing of burnsThe effect of Oral Centella Asiatica on pain and wound healing of burnsIRCT20181229042166N1
Pharmacokinetics Centella Asiatica Product (CAP) in Mild Cognitive ImpairmentA Pharmacokinetic Study of Centella Asiatica Product (CAP) in Elderly Participants With Mild Cognitive Impairment Receiving Cholinesterase Inhibitor TherapyNCT03937908
Clinical trial on eye health in healthy elderly volunteers.A Prospective, Double Blind, Randomized, Placebo Controlled Interventional Study, to evaluate Safety and Efficacy of Centella Asiatica Extract tablets in Improving MPOD Levels in Elderly Volunteers.CTRI/2019/05/019392
A clinical study to evaluate the safety and efficacy of test drug in improving liver health disease.A randomized, double blind, placebo controlled, parallel study to evaluate the comparative efficacy and safety of centella asiatica extract tablet with that of a placebo tablet in improving ALT levels in subjects with elevated ALTCTRI/2019/08/020878
Topical Centella Asiatica and the Cosmetic Appearance of Stretch MarksTopical Centella Asiatica and the Cosmetic Appearance of Stretch MarksNCT02601105
The effect of a centella asiatica containing repair mask as an adjuvant and preventive treatment for rosaceaThe effect of a centella asiatica containing repair mask as an adjuvant and preventive treatment for rosaceaChiCTR1900026527
Therapeutic efficiency and safety assessment of Centella asiatica capsule in patients with non-alcoholic steatohepatitis (NASH) in ThailandTherapeutic efficiency and safety assessment of Centella asiatica capsule in patients with non-alcoholic steatohepatitis (NASH) in ThailandTCTR20221215002
The Effect of New Dentifrices Containing Centella Asiatica and Bamboo Salt on Reducing Plaque and GingivitisThe Effect of New Dentifrices Containing Centella Asiatica and Bamboo Salt on Reducing Plaque and Gingivitis: a Randomized Clinical TrialNCT02616042
Homoeopathy in VitiligoComparative Effectiveness of Individualized Homoeopathic Medicine and Hydrocotyle asiatica in the treatment of Vitiligo in Paediatric age group – an Open-label, Randomised, Clinical trial - NILCTRI/2024/03/063945
Safety and Target Engagement of Centella Asiatica in Cognitive ImpairmentSafety and Target Engagement of Centella Asiatica in Cognitive ImpairmentNCT05591027
Effects of dietary Centella asiatica extract on cognition and oxidative stress markers in elderly with mild cognitive impairmentEffect of dietary Centella asiatica extract on cognition and oxidative stress markers: A Double-blinded Randomized Placebo-Controlled Trial.TCTR20180228001
Centella asiatica extract on the prevention of radiation-induced dermatitis in breast cancer patientsComparison of the effectiveness of administration of Centella asiatica extract in comparison with placebo on the prevention of radiation-induced dermatitis in breast cancer patientsIRCT20211231053576N1
The effect of herbal ointment containing centella asiatica on third degree burning woundThe effect of Centella asiatica ointment on third degree burns in patients to the burn center of burns in the province of Rasht in 2018IRCT20131006014915N2
Effect of Centella Asiatica on intestinal microbiota and protein-binding toxins in patients with chronic kidney disease stage 4-5Effect of Centella Asiatica on intestinal microbiota and protein-binding toxins in patients with chronic kidney disease stage 4-5ITMCTR2025000700

Phytochemicals present in Centella asiatica


Indian medicinal plantPlant partIMPPAT Phytochemical identifierPhytochemical nameReferences
Centella asiaticaIMPPAT3_PHYID000002D-GlucoseISBN:9788185042053
Centella asiaticaIMPPAT3_PHYID000007QuercetinPMID:17473438, PMID:20492146, PMID:21353543
Centella asiaticaIMPPAT3_PHYID000013L-RhamnoseISBN:9788185042053, ISBN:9788185042145
Centella asiaticaIMPPAT3_PHYID000018beta-SitosterolISBN:9788172361150, PMID:20143295
Centella asiaticaIMPPAT3_PHYID000022alpha-CopaeneDOI:10.15482/usda.adc/1239279
Centella asiaticaIMPPAT3_PHYID000023beta-CaryophylleneISBN:9788172361150
Centella asiaticaIMPPAT3_PHYID000024HumuleneDOI:10.15482/usda.adc/1239279
Centella asiaticaIMPPAT3_PHYID000025(S,1Z,6Z)-8-Isopropyl-1-methyl-5-methylenecyclodeca-1,6-dieneISBN:9788172361150
Centella asiaticaIMPPAT3_PHYID000065alpha-CaroteneISBN:9788172361150
Centella asiaticaIMPPAT3_PHYID000075Oleic acidPMID:18688644
Centella asiaticaIMPPAT3_PHYID000085MyricetinPMID:20492146
Centella asiaticaIMPPAT3_PHYID000098CampesterolISBN:9788172361150
Centella asiaticaIMPPAT3_PHYID000112beta-FarneseneISBN:9788172361150
Centella asiaticaIMPPAT3_PHYID000140StigmasterolISBN:9788172361150, PMID:20143295
Centella asiaticaIMPPAT3_PHYID000149Ursolic acidPMID:15635187
Centella asiaticaIMPPAT3_PHYID000153alpha-PineneDOI:10.15482/usda.adc/1239279
Centella asiaticaIMPPAT3_PHYID000156ApigeninPMID:20492146
Centella asiaticaIMPPAT3_PHYID000188L-(+)-ArabinoseISBN:9788185042053
Centella asiaticaIMPPAT3_PHYID000227alpha-TerpineolDOI:10.15482/usda.adc/1239279
Centella asiaticaIMPPAT3_PHYID000230Thymol methyl etherISBN:9788172361150
Centella asiaticaIMPPAT3_PHYID000251KaempferolPMID:17473438, PMID:20492146, PMID:21353543
Centella asiaticaIMPPAT3_PHYID000266LuteolinPMID:20492146
Centella asiaticaIMPPAT3_PHYID000281AstragalinPMID:21353543
Centella asiaticaIMPPAT3_PHYID000282IsoquercitrinPMID:21353543
Centella asiaticaIMPPAT3_PHYID000304Ascorbic acidDOI:10.15482/usda.adc/1239279, ISBN:9788172361266
Centella asiaticaIMPPAT3_PHYID0003254-MethoxybenzaldehydePMID:16206136
Centella asiaticaIMPPAT3_PHYID000340Betulinic acidISBN:9788172361150
Centella asiaticaIMPPAT3_PHYID000365Quercetin-3-glucosidePMID:17473438
Centella asiaticaIMPPAT3_PHYID000392Chlorogenic acidPMID:17473438, PMID:21635941
Centella asiaticaIMPPAT3_PHYID000615alpha-TerpineneISBN:9788172361150
Centella asiaticaIMPPAT3_PHYID000623CupareneDOI:10.15482/usda.adc/1239279
Centella asiaticaIMPPAT3_PHYID0014722,3-DihydrobenzofuranDOI:10.15482/usda.adc/1239279
Centella asiaticaIMPPAT3_PHYID001548Corosolic acidPMID:15635187
Centella asiaticaIMPPAT3_PHYID004068Cyclohexanecarboxylic acid, 3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxy-, (1S,3R,4S,5R)-PMID:18404308
Centella asiaticaIMPPAT3_PHYID004654Pomolic acidPMID:15635187
Centella asiaticaIMPPAT3_PHYID0056822-Methyl-2-butanolDOI:10.15482/usda.adc/1239279
Centella asiaticaIMPPAT3_PHYID005885BayogeninPMID:17802882
Centella asiaticaIMPPAT3_PHYID006194Asiaticoside AISBN:9788171360536, ISBN:9788172360481, ISBN:9788172361150, ISBN:9788183602525, ISBN:9788185042053, ISBN:9788185042114, ISBN:9789327275590, PMID:11605675, PMID:18503551, PMID:19924039, PMID:20143295
Centella asiaticaIMPPAT3_PHYID006195AsiaticosideISBN:9780387706375, ISBN:9788171360536, ISBN:9788172360481, ISBN:9788172361150, ISBN:9788172361266, ISBN:9788183602525, ISBN:9788185042114, ISBN:9789327275590
Centella asiaticaIMPPAT3_PHYID006196Madecassic acidISBN:9788171360536, ISBN:9788172360481, ISBN:9788185042053, ISBN:9789327275590, PMID:11605675, PMID:14531023, PMID:20143295, PMID:2354631, PMID:4961798
Centella asiaticaIMPPAT3_PHYID006197Asiatic acidDOI:10.15482/usda.adc/1239279, ISBN:9788171360536, ISBN:9788172360481, ISBN:9788172361150, ISBN:9788185042053, ISBN:9788185042145, ISBN:9789327275590, PMID:1367880, PMID:14531023, PMID:15635187, PMID:18279797, PMID:20143295, PMID:20839122, PMID:21167268, PMID:21353543, PMID:22506133, PMID:2354631
Centella asiaticaIMPPAT3_PHYID006198Isothankunic acidISBN:9788172361150, ISBN:9788185042053
Centella asiaticaIMPPAT3_PHYID006199(1S,2R,4aS,6aR,6aS,6bR,8R,8aR,10R,11R,12aR,14bS)-8,10,11-trihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acidISBN:9788185042084, PMID:11605675
Centella asiaticaIMPPAT3_PHYID006200Unii-CQ2F5O6yiyISBN:9788185042145
Centella asiaticaIMPPAT3_PHYID006201TerminolosideISBN:9788185042145
Centella asiaticaIMPPAT3_PHYID006202(2-Hydroxy-4,6-dimethoxyphenyl)-phenylmethanoneISBN:9788171360536, ISBN:9788172361266
Centella asiaticaIMPPAT3_PHYID006203alpha-ChamigreneDOI:10.15482/usda.adc/1239279
Centella asiaticaIMPPAT3_PHYID006206AnthronePMID:13990461, PMID:14048142
Centella asiaticaIMPPAT3_PHYID006207Gulonic acidPMID:17802882
Centella asiaticaIMPPAT3_PHYID006208DammaranePMID:21751844
Centella asiaticaIMPPAT3_PHYID006209GinsenosidesPMID:21751844
Centella asiaticaIMPPAT3_PHYID006210quadranoside IVPMID:21353543
Centella asiaticaIMPPAT3_PHYID006211Rosmarinic acidPMID:15635187
Centella asiaticaIMPPAT3_PHYID006212Ursolic acid lactonePMID:15635187
Centella asiaticaaerial partIMPPAT3_PHYID000023beta-CaryophylleneDOI:10.1080/10412905.1994.9698382, ISBN:9788172362089
Centella asiaticaaerial partIMPPAT3_PHYID000024HumuleneDOI:10.1080/10412905.1994.9698382, ISBN:9788172362089
Centella asiaticaaerial partIMPPAT3_PHYID000025(S,1Z,6Z)-8-Isopropyl-1-methyl-5-methylenecyclodeca-1,6-dieneDOI:10.1080/10412905.1994.9698382, ISBN:9788172362089
Centella asiaticaaerial partIMPPAT3_PHYID000046LimoneneDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID0000812-Methoxy-4-vinylphenolDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID000095FarnesolDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID000108HexanalDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID000112beta-FarneseneDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID000114NerolidolDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID000153alpha-PineneDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID000159beta-PineneDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID000163CampheneDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID000213MyrceneDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID000220gamma-TerpineneDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID000226LinaloolDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID000227alpha-TerpineolDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID000242Caryophyllene oxideDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID000256GeraniolDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID000417NerolDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID000440HeptanalDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID0004412-HeptenalDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID0004432-OctenalDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID000463(+)-delta-CadineneDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID000467epi-GlobulolDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID000526beta-BisaboleneDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID0006303-(1,5-Dimethyl-4-hexenyl)-6-methylene-1-cyclohexeneDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID000677(-)-beta-ChamigreneDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID001109FurfuralDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID0014722,3-DihydrobenzofuranDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID001548Corosolic acidISBN:9770976605004
Centella asiaticaaerial partIMPPAT3_PHYID001863PentanalDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID002473TolueneDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID003263m-XyleneDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID0034563-Nonen-2-oneDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID0056822-Methyl-2-butanolDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID0062043-Hexen-2-oneDOI:10.1080/10412905.1994.9698382
Centella asiaticaaerial partIMPPAT3_PHYID006205(E)-5-Nonen-2-oneDOI:10.1080/10412905.1994.9698382
Centella asiaticaleafIMPPAT3_PHYID006195AsiaticosideISBN:9788172361266
Centella asiaticawhole plantIMPPAT3_PHYID000018beta-SitosterolISBN:9788172361266
Centella asiaticawhole plantIMPPAT3_PHYID006194Asiaticoside AISBN:9788190648943
Centella asiaticawhole plantIMPPAT3_PHYID006195AsiaticosideISBN:9788190648943
Centella asiaticawhole plantIMPPAT3_PHYID006196Madecassic acidISBN:9788172360481, ISBN:9788190648943
Centella asiaticawhole plantIMPPAT3_PHYID006197Asiatic acidISBN:9788190648943